USE or U.S.E. can refer to:
- United States of Europe, a term sometimes used to refer to a hypothetical Federal Europe
- The fictional United States of Europe in the alternate history novel 1632 and the following 1632 book series
- United State of Electronica, an American rock band
- U.S.E. (album), a self-titled album by the band
- Uganda Securities Exchange, the principal stock exchange in Uganda
- Uzbekistan Stock Exchange
Community content is available under CC-BY-SA unless otherwise noted.